Hygiene Atlas

Atlas · Plate X · Periodontology · 05

Chemotherapeutic agents

Chlorhexidine 0.12%, essential oil and cetylpyridinium chloride rinses help control gingivitis; chlorhexidine stains and is inactivated by sodium lauryl sulfate. Locally delivered minocycline, doxycycline gel and the chlorhexidine chip go into pockets of 5 mm or more after scaling. Subantimicrobial-dose doxycycline modulates the host by inhibiting collagenase rather than killing bacteria.

High-yield facts · 8

  1. Chlorhexidine gluconate 0.12%: 15 mL rinse for 30 s twice daily; substantivity about 8-12 hours; stains teeth, alters taste, increases supragingival calculus.T2
  2. Wait about 30 min between toothpaste with sodium lauryl sulfate and chlorhexidine because SLS inactivates it.T2
  3. Essential oil rinses and cetylpyridinium chloride rinses are ADA-accepted antigingivitis agents.T2
  4. Minocycline microspheres (1 mg per site) are placed into pockets of 5 mm or more after scaling.T3
  5. Doxycycline hyclate 10% gel is a locally delivered biodegradable antibiotic.T3
  6. The chlorhexidine chip holds 2.5 mg chlorhexidine and is inserted into pockets of 5 mm or more.T3
  7. Subantimicrobial-dose doxycycline 20 mg twice a day for up to 9 months inhibits collagenase (host modulation).T3
  8. Systemic antibiotics (e.g., amoxicillin plus metronidazole) are reserved for severe or rapidly progressing (grade C) cases.S38

Facts are written in our own words; each tag links to its source. Values marked "sources vary" differ between references, so check the one your program uses.